141–160 of
190 results.
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Winni Agustiani
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Mansyur Arif
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Ilhamjaya Patellongi
BACKGROUND: Inflammation in the vascular wall plays an important role in the pathogenesis of atherosclerosis. Current studies have shown that increase of systemic inflammatory marker like the acute ph...
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Antonia Anna Lukito
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Allen Widyasanto
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Trilis Yulianti
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Rusli Muljadi
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Andi Wijaya
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2 more
• Peter Kabo
• Syakib Bakri
BACKGROUND: Previous studies have confirmed separately the relationship between obesity, insulin-resistance, hypertension and bone morphogenetic protein-2 (BMP-2) with coronary artery calcification, a...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: The ability to reprogram mature cells to an embryonic-like state by nuclear transfer or by inducing the expression of key transcription factors has provided us with critical opportunities ...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: Increasing prevalence of obesity gives rise to many problems associated with multiple morbidities, such as diabetes, hypertension, heart disease, sleep apnea and cancer. The mechanism of o...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: Less than a decade ago the prospect for reprogramming the human somatic cell looked bleak at best. It seemed that the only methods at our disposal for the generation of human isogenic plur...
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Andri Hidayat
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Andi Wijaya
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Harun Alrasyid
BACKGROUND: Many studies have shown that obesity was closely related to insulin resistance via several pathways such as inflammation, oxidative stress, lipolysis, and endothelial dysfunction. This stu...
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Sri Andarini
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Djanggan Sargowo
BACKGROUND: Obesity, especially obesity in adolescent, is a worldwide health problem needing much of our attention because it can continue to be obesity in adulthood. About 50% obese adolescents grew ...
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Anna Meiliana
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Andi Wijaya
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Suryani As'ad
BACKGROUND: The increased prevalence of obesity worldwide is correlated with increasing prevalence of metabolic syndrome. Studies of adipose tissue have been improved from an inert energy storage to a...
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Bambang Purwanto
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A. Guntur Hermawan
BACKGROUND: Use of doxorubicin (DXR) in the treatment of cancer has been increasing along with the increase in cancer morbidity. Nephrotoxic effects of DXR are still a problem. Pentoxyphylline (PTX) a...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: Human fat consist of white and brown adipose tissue (WAT and BAT). Though most fat is energy-storing WAT, the thermogenic capacity of even small amounts of BAT makes it an attractive thera...
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Ferry Sandra
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Roya Khosravi-Far
BACKGROUND: Survivin is rarely expressed in normal healthy adult tissues, however, it is upregulated in the majority of cancers. Survivin, which belongs to IAPs family, has been widely reported to pro...
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Candra Ninghayu
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Andi Wijaya
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Suryani As'ad
BACKGROUND: Obesity raises the risk for atherosclerotic cardiovascular disease (ASCVD) through many risk factors including atherogenic dyslipidemia. Atherogenic dyslipidemia is characterized by high l...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: There is probably no single way to age. Indeed, so far there is no single accepted explanation or mechanisms of aging (although more than 300 theories have been proposed). There is an over...
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Trilis Yulianti
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Mansyur Arif
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Andi Wijaya
BACKGROUND: Adult obesity is rapidly increasing in the world including Indonesia. Tumor necrosis factor α (TNF-α) was chronically elevated in obese adipose tissue. TNF-α, a pleiotropic cytokine and al...
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Ida Paulina Sormin
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Widjaja Lukito
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Andi Wijaya
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Suryani As'ad
BACKGROUND: Biogenesis of HDL involves factors that regulate the synthesis, intravascular remodeling, and catabolism of HDL. Disturbance of these factors can lead to low concentration of HDL-C. Metabo...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: Epidemiological data reveal parallel trends of decreasing sleep duration and increases in metabolic disorders such as obesity, diabetes and hypertension. There is growing evidence that the...
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Maria Diah Fibriani
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Andi Wijaya
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Burhanuddin Bahar
BACKGROUND: Obesity has a central role in the metabolic syndrome, which raises the risk for atherosclerotic cardiovascular disease (ASVCD). Apo B-48 and Apo B-100 are the necessary structural proteins...
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Anna Meiliana
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Andi Wijaya
BACKGROUND: The investigation of novel circulating serum and plasma biomarkers in patients with cardiovascular disease has been accelerating at a remarkable pace. New markers or tests are often presen...
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Rini Budiyati
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Widjaja Lukito
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Andi Wijaya
BACKGROUND: Visfatin is a novel adipokine secreted from visceral adipose tissue and has insulinomimetic properties. Visceral obesity is a risk factor for metabolic syndrome. Insulin resistance and inf...
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Waode Nurfina
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Irawan Yusuf
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Mansyur Arif
BACKGROUND: The low inflammatory state that accompanies the Metabolic Syndrome (MetS) associates with the overexpression of oxidative stress. Ferritin and Transferrin serum are often used to measure i...