Mother and child health is the third target of SDGs, namely ensuring a healthy life and encouraging welfare for all people at all ages. The class of pregnant women is part of the Maternal and Child Health Program that has been carried out since 2009. The purpose of this study is to assess the effectiveness of the implementation of classes of pregnant women towards the knowledge and attitude of early detection of high risk factors in the Work Area of the Lalowaru Health Center, Konawe Selatan District. The method in this study uses quasi-experimental. The treatment group was given an intervention in the form of education using a pocket book for 6 months (starting from the second trimester of pregnancy to the third trimester of pregnancy). The control group did not receive education and a pocket book. The research sample consisted of 40 respondents consisting of an intervention group of 20 people and a control group of 20 people. Data analysis uses the Wilcoxon signed test. The results showed that education increased the knowledge of pregnant women about early detection of pregnancy (mean posttest intervention group: 92.69 ± 0.96 (p-value = 0,000)). Education improves the attitude of pregnant women regarding early detection of pregnancy (mean posttest intervention: 96.36 ± 0.84 (p-value = 0,000)). Education increases the ANC visit of pregnant women regarding early detection of pregnancy (p-value = 0,000).