Relevance of the topic. Genital prolapse remains a pressing problem of operative gynecology, as it is characterized by a highrelapse rate of the disease after surgical treatment. This article compares 2 surgical methods for the prevention of vaginal vaultafter total hysterectomy in obese women. Purpose. Development of an effective method for preventing vaginal vault prolapse by improving the surgical technique of total hysterectomy in obese women. Materials and methods. The main group included 178 obese patients with BMI from 30 to 40, who underwent the operation of extirpation of the uterus with laparotomic access using an improved technique for strengthening the vaginal vault. The comparison group included 104 patients also with obesity, BMI from 30 to 40, with extirpation of the uterus by laparotomic access with suturing vaginal vault in traditional method. The results of the study. The duration of the total hysterectomy operation using the advanced technology varied from 45 to 75 minutes, on average 52.5+1.5 minutes. With the traditional method, the operation of abdominal total hysterectomy lasted from 90 to 110 minutes, 98.6 ±5.6 minutes, (p<0.05). Thus, in the main group, it averaged 52.5+1.5 minutes, which was significantly shorter than in the comparison group - 98.6 ±5.6 minutes, (p<0.05).