This research entitled learning potential of physical and psychological according to Al-Qurâ€™an 16:17(study of interpretation of Islamic education). The problems of the research are 1. Based on Alqurâ€™â€™an, An Nahl 78, how student physic and psychology potential learning in specific as well as human being . 2 What learning potential owned by human being dealing with the developing process in term of psychological aspect and study of interpretation of Islamic education. This library research applies contextual method through reading, observing, and adapting with discussion material. Then it will be explained in discussion by applying deductive and inductive method. The research concludes that men are perfect human being blessing with some potential to learn everything. They are the best of Allah creation of all. Allah in Al-Qurâ€™an suggest all men to learn and get studying due to lead them into his bless. Not merely blessing with goodness, Allah give them with lust that lead into badness. Therefore, education leads the human being to do some goodness. It can be gained through teaching and education process between pupil and teacher.